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Interviews touching on seed-related Intellectual Property Protection

On Genetic Use Restriction Technologies (GURTs)

Dr. Harry B. Collins
Vice President, Technology Transfer
Delta and Pine Land Company
USA

Dr. Harry B. Collins is Vice President of Technology Transfer for Delta and Pine Land Company, a world leader in cotton planting seed. The technology protection system patented by D&PL and the USDA is one of Dr. Collins' primary responsibilities. He has been with D&PL since joining the company in 1974 as soybean breeder, later becoming Deltapine's Vice President of Research. In this research leadership role, Dr. Collins oversaw the introduction of transgenic traits into D&PL's elite germplasm.
This past year, Dr. Collins was appointed to the USDA's Plant Variety Protection Advisory Board. He is a member of the CropLife America biotech committee. He is active in the American Seed Trade Association, where he recently served as chair of the biotechnology committee and where he is an active member of the Intellectual Property Protection Committee.
Dr. Collins has a PhD in genetics and plant breeding from North Carolina State University in Raleigh, a Master's degree in agronomy and plant breeding from the University of Arizona at Tucson and a Bachelor's degree from Rutgers University in New Brunswick, New Jersey.

What are Genetic Use Restriction Technologies (GURTs)?
Are there different types of GURTs?

Genetic Use Restriction Technologies (GURTs) are transgenic technologies, which either control the germination of seed or the expression of specific traits in plants.
There are two main types of GURTs. They are V-GURTs and T-GURTs.
V-GURTs are varietal GURTs that, once triggered, would cause the grain or seed on the farmer’s crop to be normal in size, but unable to germinate, if saved for seed.
T-GURTs or trait GURTs, generally, when triggered in the farmer’s field would cause the plants to express a specific trait, such as insect resistance. The T-GURT trait would only be triggered to express a trait when that specific trait is needed in a particular growing season and this trait would only be paid for when needed and used.

What has led to the development of these Genetic Use Restriction Technologies?

One reason for developing GURTs was the need for biosafety in transgenic plants, which will prevent the escape of transgenes to non-transgenic crop plants of the same species or the improbable, but possible escape of transgenes from crop plants to closely-related wild species.
A second reason for developing GURTs is the need for a physical means of providing intellectual property protection (IPP) in crop species in which there have been few incentives for breeding research investments because of seed saving by farmers, which prevents the recouping of research investments after one sale of seed.

How can these technologies impact the seed industry and agriculture in general?

GURTs could increase research investments in crop species and geographies that historically have received little breeding attention from seed firms because of the lack of opportunities to recoup research investments due to seed saving.
The increased competition among seed companies in markets previously given minimal breeding attention could provide farmers with more improved varieties and technologies. These new varieties could provide higher yield potentials and more and improved pest resistance.

Who are the opponents of GURTs, and what arguments do they put forward?

Some non-government organizations (NGOs) have opposed the introductions of GURTs and have convinced organizations in other parts of the world, especially in developing countries that GURTs should be banned. Some of the reasons given for opposing GURTs follow; 1. They would restrict poor farmers' access to new varieties and technologies, 2. They would restrict poor farmers' access to new, advanced germplasm with which to make crosses and develop locally adapted varieties, 3. They could cause crises if seed supplies are low due to poor seed production the previous year, 4. They could cause seed production problems if pollen from a V-GURT variety grown in a field next to a non-V-GURT field caused sterile seed in the non-V-GURT field.
We disagree with these viewpoints and feel science proves our position whereas our opponents use only anecdotal information and fear to support their positions. It should be noted that there has been very little negative reaction to GURTs in the United States and several crop commodity groups in the U.S. have encouraged the development of GURTs for biosafety applications.

Who are the proponents of GURTs, and what arguments do they put forward?
Scientists, both in the U.S. and in other parts of the world have expressed interest in using V-GURTs to prevent the unwanted movement of transgenes from transgenic plants to other plants.
Many seed companies, both large and small, have shown interest in GURTs, both for the biosafety they would provide and the Intellectual Property Protection (IPP).
As stated earlier, it is believed that GURTs would have the effect, with the increased Intellectual Property Protection, of encouraging investments in breeding and biotechnology research in crops and geographies not addressed in the past because of a lack of full Intellectual Property Protection.

What issues are these technologies facing at the international level?

There have been attempts to ban GURTs in the FAO and the CBD. Small farmers in developing countries and indigenous people are used by NGOs as examples of farmers who will be hurt by GURTs, mainly because, it is asserted the small farmers will not be able to save seed and will not be able to make crosses to newly introduced GURT varieties to develop new land races.
Proponents of GURTs have argued that these small farmers should have choices available to them as to whether they want to grow GURT varieties if they gain advantages from these varieties that will offset the fact that they cannot save.
The primary objective of farmers should be to increase production and profit, not to be able to save seed at the expense of productivity. We believe, given the choice, farmers will choose improved varieties and technologies. However, it will be the farmers’ choice.

What are, in your opinion, the justifications for implementing GURTs?

Biosafety and Intellectual Property Protection, with its subsequent advantages to the farmer customers in providing them with improved varieties for greater efficiencies of production. 

Describe the Technology Protection System (TPS) which is jointly owned by USDA-ARS and Delta and Pine Land Company.

TPS is a transgenic system comprised of a complex array of genes and promoters which, in the normal state, are inactive. This means the plants are normal and produce normal seeds which will germinate. However, when the seeds which are sold to the farmer are treated with a chemical prior to bagging, it triggers, at the time of germination, an irreversible series of genetic events. Once this system has been activated, the plants that the farmers grow are normal and produce normal appearing, fully developed seed. Because of the removal of a blocker between a Late Embryogenesis Abundant promoter (LEA) and a germination disruptor gene, the seed produced on the farmers’ plants are rendered nonviable at dry down time.
It is important that normal, fully developed seeds are produced. With many crops, these seeds, or products of these seeds, are the commodities which the farmer is producing and for which he is paid. Some targeted crops include cotton, soybeans, wheat and rice.

What are the benefits of the Technology Protection System (TPS)?

1) Biosafety
The prevention of the very improbable but, possible escape of transgenes, through pollen, from a crop plant to plants of a closely related wild species
The prevention of transgenes escaping to non-transgenic plants of the same crop species through pollen.
Volunteer seed which drop to the ground will not germinate.

2) TPS would protect North American farmers from unfair competition due to large agricultural countries obtaining new technologies free of charge, when North American farmers are paying for the technologies

3) Intellectual Property Protection
Because there would be a return on investment, TPS should;
Encourage research investment in breeding research
Increase incorporation of transgenes in varieties
This would be beneficial to large and small farmers, in developed and underdeveloped countries, by providing them with more new and advanced products

4) TPS would probably prevent grains from germinating in the heads under warm wet conditions, thus reducing a major cause of poor grain quality and subsequent economic losses.

Annex: Position Paper of the International Seed Federation on Genetic Use Restriction Technologies (GURTs) (June 2003)

What would you like the readers to know about your company?

Delta and Pine Land Company is a customer-focused commercial breeder, producer and marketer of cotton planting seed, as well as soybean seed in the U.S. Cotton Belt. For almost 90 years, the Company has used its extensive cotton plant breeding programs drawing from a diverse germplasm base to develop improved varieties. Delta and Pine Land (NYSE: DLP), headquartered in Scott, Mississippi, has offices in eight states and facilities in several foreign countries.

Delta and Pine Land Company is at www.deltaandpine.com 
Dr. Harry Collins can be reached at Harry.B.Collins@deltaandpine.com 

Sponsored by Jondle & Associates P.C. - Specialists in Intellectual Property Law

 


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