Wageningen, The Netherlands
January 12, 2009
The Whole Genome Profiling (WGP)
method enables the de novo construction of a complete high
quality physical map. This sequence-based physical map forms the
framework to construct a complete genome sequence assembly of
plant and animal genomes in a fast and cost-effective manner.
The automated and robotized BAC pooling strategies of
Amplicon Express combined
with Keygene's next
generation sequencing strategies and dedicated software tools,
made it possible to generate a high resolution assembly of the
450 Mbp melon genome.
At the 16th annual Plant and Animal Genome conferences held in
San Diego, USA from January 10 through January 14, 2009, KeyGene
and Amplicon Express will announce this new method. "Combining
the expertise and innovative capacity of both Amplicon Express
and KeyGene provide Life Sciences researchers a new and exciting
method for fast and high quality genome assembly and sequencing
that will boost genome and gene function research considerably"
says Arjen van Tunen, CEO of KeyGene. "Both KeyGene and Amplicon
Express are committed to roll out this novel proprietary method
in a fast and broad way."
"Fast genome sequencing and assembly provides big opportunities
for the seed and Ag Biotech industry. This assists them in
developing innovative, genetically improved crop varieties that
have superior traits providing benefits for the consumers,
retailers and producers' states Michiel van Eijk, vice president
Upstream Research of KeyGene and responsible for the development
of the new method. 'Until now having fast access to complete
genome sequences was not always possible because of the high
investments and time consuming procedures involved. With our new
method we offer a solution for complete genome assembly. KeyGene
and Amplicon Express can offer this now using their proprietary
state of the art BAC pooling, High Throughput Sequencing and
Bioinformatics platforms."
"KeyGene and Amplicon Express will combine marketing/sales
forces and technical support teams dedicated to offering Whole
Genome Profiling as a service" says Robert Bogden, CEO of
Amplicon Express. Our collaboration will ensure a fast, world
wide distribution of the WGP method"
Keygene N.V. is a R&D
company with the mission to be the leading company in developing
and applying DNA expertise in the field of molecular genetics
with a focus on crop plants. In recent years KeyGene invested in
next generation sequencing platforms to support its leading
position in the field of plant molecular breeding and developed
several new enabling technologies. KeyGene exploits its
proprietary technologies, databases and know-how through
strategic alliances, contract research and products for
applications in the plant breeding industry. KeyGene has a
subsidiary in Rockville Maryland, USA and a Joint Lab at the
Shanghai Institute of Biological Sciences in Shanghai, China. In
total KeyGene employs 130 researchers and staff.
Amplicon Express Inc. is focused on making high quality products
and services for genome researchers
including custom BAC libraries and BAC DNA pooling strategies
designed for Next Gen sequencing systems.
Applications for trademark registration for KeyGene have been
filed by Keygene N.V
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