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Valent BioSciences and Chengdu Institute of Biology to collaborate on crop stress management research

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Libertyville, Illinois
March 19, 2008

Valent BioSciences Corporation (VBC) has signed a five-year collaborative agreement with the Chengdu Institute of Biology (CIB) of the Chinese Academy of Sciences to study the role of abscisic acid (s-ABA) in crop stress management and plant disease resistance.

The research and development initiative will seek to clarify the mode of action of abscisic acid in disease resistance and to generate further understanding of its physiological function in plants. VBC and CIB believe this research will ultimately lead to commercial applications that overcome crop stress due to diseases and other factors.

“This collaboration combines the research strengths of the Chengdu Institute of Biology of the Chinese Academy of Sciences and the global research and commercial development expertise of Valent BioSciences,” says Dr. Wu Ning, director of CIB.

Leadership in abscisic acid development

Abscisic acid – one of the five classes of plant growth regulators naturally present in plants – regulates numerous plant processes, including responses to stress conditions, dormancy, maturation, abscission and growth.

“ABA plays a key role in plant growth and development, and our laboratory is interested in studying the effects of s-ABA on plant disease resistance,” Professor Tan Hong, key scientist at CIB. “Our work shows effects of abscisic acid are dependent on the plant pathogen system – both in expression of plant diseases, as well as resistance.”

Valent BioSciences has significant experience with s-ABA as well, investing substantial research and development resources, and establishing a strong intellectual property position over the past few years. “Given the significant progress on applied research with s-ABA achieved by VBC and CIB, there is an opportunity for s-ABA to be developed further for both high-value and traditional row-crop agriculture,” says Michael Donaldson, president and chief operating officer of Valent BioSciences.

Plant frowth regulators, microbials for crop stress management

Donaldson says the agreement is consistent with Valent BioSciences’ overall strategy to develop biorational plant growth regulators and microbial agents for crop stress management. “There is increasing understanding of the need to overcome both biotic and abiotic stress in agricultural production,” Donaldson says. “While other companies are using genetic modification to develop crop stress management solutions, Valent BioSciences is developing solutions based on biorational products for seed and plant applications.” This includes existing commercial applications of aminoethoxyvinylglycine (AVG), which inhibits ethylene biosynthesis, as well as applications of Myrothecium verrucaria for plant root health.

Valent BioSciences Corporation, headquartered in Libertyville, Illinois (USA), is a worldwide leader in the research, development and commercialization of low-risk, environmentally compatible technologies and products for the agricultural, public health, forestry and household insecticide markets. For more information on Valent BioSciences Corporation and its products, please visit www.valentbiosciences.com.

Chengdu Institute of Biology (CIB), Chengdu, China, is a premier institution within the Chinese Academy of Sciences (CAS).CIB is known for implementing the Knowledge Innovation Programme of the CAS, which aims to promote the innovative capacity of its affiliated research institutes through key input in human resources and research funds. CAS has significant accomplishments in the area of plant science research and environmental microbiology.

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