Norwich, United Kingdom
March 6, 2006
What have
Black-eyed peas got to do with nanotechnology? As well as
sharing their name with a chart-topping U.S. band, Black-eyed
peas (also known as Cowpeas) are being used by scientists at
the
John Innes Centre
in Norwich (JIC) [1] to grow virus particles that can be
decorated with a chemical turning the particles into a kind of
molecular capacitor.
Nanotechnology is the study of tiny structures in the scale of
1/100,000 of the width of a human hair and crosses the
disciplines of chemistry, biology and physics. This work has
been published in the journal “Small” [2] and is the first piece
of nanotechnology from the John Innes Centre. The researchers at
the institute are using a harmless virus of Cowpea plants
because its tiny size and unique structure makes it an ideal
scaffold for decoration with various chemicals to give different
characteristics, depending on the application required [3].
“This is an
exciting discovery in bionanotechnology, at the interface of
chemistry and biology, using plant viruses to produce
electronically active nanoparticles of defined size” says Nicole
Steinmetz, a PhD student working on the EU-funded project [4] in
the group of Dr Dave Evans (Project Leader)
in collaboration with Dr. George Lomonossoff in the
Department of Biological Chemistry, “Future applications may be
in, for example, biosensors, nanoelectronic devices, and
electrocatalytic processes.”
Professor
Chris Lamb, Director, JIC said "The combination of expertise
from different disciplines, in this case plant virology and
chemistry, is one of strengths of the John Innes Centre, with
long term fundamental research programmes underpinning exciting
innovations that can lead to discoveries such as this."
This
project is still in the very early stages, but the scientists
hope that this groundbreaking research will lead to the
development of the technology for use in medical as well as
industrial applications.
[1] The
John Innes Centre (JIC),
Norwich, UK is an independent, world-leading research centre in
plant and microbial sciences. The JIC has over 800 staff and
students. JIC carries out high quality fundamental, strategic
and applied research to understand how plants and microbes work
at the molecular, cellular and genetic levels. The JIC also
trains scientists and students, collaborates with many other
research laboratories and communicates its science to end-users
and the general public. The JIC is grant-aided by the
Biotechnology and Biological Sciences Research Council.
[2] This work was published in Small (2006) 4, 530 - 533.
(Publishers: Wiley InterScience).
[3] The Cowpea mosaic virus has characteristics of an ideal
nanoscaffold/building block. It has a sphere-like structure of
28 nm diameter and its properties are defined. The virus
particles can be obtained in gram scale from 1 kg of infected
plant leaves. Amino acids on the exterior surface of the virus
particle provide sites of attachment for a range of chemicals.
[4] This work is funded by the EU Marie Curie Early Stage
Research Training Scheme that provides funding for PhD students
in the European Union. |