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February 25, 2009
Genedata, a leading provider of in-silico solutions for
pharmaceutical R&D and related life sciences, today announced
the extension of a biomarker discovery collaboration with
Syngenta, a leading global
agrochemical company. Syngenta has added the Genedata
Expressionist Refiner MS module for LC-MS and GC-MS metabolomic
raw data processing and analysis to their existing Genedata
Expressionist system. Refiner MS expands Expressionist to
process and analyze metabolomic raw MS data separately and in
conjunction with microarray data, dramatically improving
efficiency and enhancing the biomarker discovery process at
Syngenta.
Syngenta has been successfully using the Genedata Expressionist
Refiner Array and Analyst modules to process and analyze
microarray data since 2005. With the rapid expansion of
metabolomics research and the associated data volumes generated,
Syngenta now uses Refiner MS to integrate MS data in their
biomarker discovery projects.
With Refiner MS Syngenta can process more rapidly and with full
confidence in quality extremely large amounts of MS data
directly from multiple hardware platforms via user defined,
flexible workflows. Peaks selection is performed automatically
in Refiner MS while statistical analysis and biological pathway
mapping are done in the powerful analytical module Analyst.
“Syngenta’s decision to use the Genedata Expressionist system
for our metabolomics research is based on the ability of Refiner
MS to capture very large data sets directly from a wide range of
instruments quickly and efficiently and to visualize and
manipulate data from a wide variety of mass spectrometry
experiment types such as GC-MS and data dependent LC-MS/MS
experiments all in one computer platform,” said Dr. David
Portwood, Head of Metabolomics at Syngenta UK. “A further major
benefit is that we can now integrate all the "omics" data types
in one platform and can perform multivariate stats within the
Analyst module avoiding time consuming exporting and importing
of data between software packages and leading, we believe, to
greater understanding and insights to the biological processes
that are key to the future success of our business.”
“We are very pleased at the continuing development of our
relationship with Syngenta, a long-term Genedata customer and a
global leader in agrochemical research,” said Dr. Othmar
Pfannes, CEO of Genedata. “The expanded use of Expressionist at
Syngenta is an excellent showcase of how Genedata’s products are
meeting specific needs today for faster and more effective
scientific exploration in a variety of life science research
processes.”
Syngenta is one of the world's leading companies with more
than 24,000 employees in over 90 countries dedicated to our
purpose: Bringing plant potential to life. Through world-class
science, global reach and commitment to our customers we help to
increase crop productivity, protect the environment and improve
health and quality of life. For more information about us please
go to www.syngenta.com.
Genedata develops and globally markets sophisticated
computational solutions for drug discovery and related research
processes in the life sciences. Genedata’s solutions enable
scientists to process, integrate, analyze, and manage large and
complex experimental data sets generated by high throughput
technologies. Solutions include Genedata Phylosopher® for target
discovery and integrative biological data management, Genedata
Screener® for automated high throughput screening and high
content screening, and Genedata Expressionist® for biomarker
discovery and personalized medicine. Founded in 1997, Genedata
is privately held, with headquarters in Basel, Switzerland, and
offices in Boston & San Francisco, USA, Konstanz & Munich,
Germany and Tokyo, Japan. For more information, please visit
www.genedata.com.
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