Date of publication: December 15,
2006
Source:
http://gmoinfo.jrc.it/gmp_browse_geninf.asp
Notification number:
B/FR/06/12/02
Member State
France
Date of Acknowledgement
10/11/2006 00:00:00
Title of the Project
Application for a multiyear program for
the deliberate release of genetically modified maize
DAS-Ø15Ø7-1, DAS-59122-7, DP-Ø9814Ø-6, DP-Ø9814Ø-6xDAS-Ø15Ø7-1,
DP-Ø9814Ø-6xDAS-Ø15Ø7-1xDAS-59122-7
Proposed period of release:
01/04/2007 00:00:00 to 31/12/2010
00:00:00
Name of the Institute(s) or
Company(ies)
Pioneer Genetique Sarl, Chemin de
l'Enseigure
31840 Aussonne;
3. Is the same GMPt release planned
elsewhere in the Community?
No
Has the same GMPt been notified
elsewhere by the same notifier?
No
Genetically modified plant
Complete name of the recipient or
parental plant(s)
|
Common Name |
Family Name |
Genus |
Species |
Subspecies |
Cultivar/breeding line |
| maize |
poaceae |
zea |
zea mays |
mays |
experimental varieties |
2. Description of the traits and
characteristics which have been introduced or modified,
including marker genes and previous modifications:
This deliberate release program
concerns three genetically modified maize, DAS-Ø15Ø7-1 (referred
to as 1507 maize), DAS-59122-7 (referred to as 59122 maize),
DP-Ø9814Ø-6 (referred to as 98140 maize), and combinations of
these maize obtained through traditional breeding methods, maize
DP-Ø9814Ø-6xDAS-Ø15Ø7-1 (referred to as 98140x1507 maize) and
DP-Ø9814Ø-6xDAS-Ø15Ø7-1xDAS-59122-7 (referred to as
98140x1507x59122 maize).
The genetically modified maize subject of this deliberate
release program are resistant to certain Lepidopteran insects,
such as European corn borer (Ostrinia nubilalis), and/or
resistant to certain Coleopteran insects, such as Western corn
rootworm (Diabrotica virgifera virgifera), and/or tolerant to
certain herbicides, containing glyphosate and acetolactate
synthase (ALS)-inhibiting herbicides such as sulfonylureas
and/or glufosinate-ammonium (tolerance to glufosinate-ammonium
in Europe is used only as a selectable marker).
Genetic modification
3. Type of genetic modification:
Insertion;
In case of insertion of genetic
material, give the source and intended function of each
constituent fragment of the region to be inserted:
· The genes introduced in 1507 maize
are the cry1F gene from Bacillus thuringiensis var. aizawai,
providing resistance to certain Lepidopteran insects and the pat
gene from Streptomyces viridochromogenes, introduced as a
selectable marker, providing tolerance to glufosinate-ammonium
herbicide, along with their regulatory components necessary for
expression in maize plant:
- The cry1F gene, the UBIZM1(2) promoter, the ORF25PolyA
terminator.
- The pat gene, the CaMV35S promoter, the CaMV35S terminator.
· The genes introduced in 59122 maize are the cry34Ab1 and
cry35Ab1 genes from Bacillus thuringiensis strain PS149B1,
providing resistance to certain Coleopteran insects and the pat
gene from Streptomyces viridochromogenes, introduced as a
selectable marker, providing tolerance to glufosinate herbicide,
along with their regulatory components necessary for expression
in maize plant:
- The cry34Ab1 gene, the UBIZM1(2) promoter, the PINII
terminator.
- The cry35Ab1 gene, the Peroxidase promoter, the PINII
terminator.
- The pat gene, the CaMV35S promoter, the CaMV35S terminator.
· 98140 maize has been genetically modified by insertion of the
glyphosate-N-acetyltransferase (gat4621) gene and a modified
maize acetolactate synthase (zm-hra) gene, along with the
necessary regulatory elements for gene expression in the maize
plant (cf confidential Annex1). The gat4621 gene encodes the
GAT4621 protein, which was derived from the soil bacterium
Bacillus licheniformis, and confers tolerance to herbicides
containing glyphosate. The zm-hra gene encodes the ZM-HRA
protein and confers tolerance to a range of ALS-inhibiting
herbicides such as sulfonylureas.
· 98140x1507 maize, obtained from traditional breeding methods
between progeny of 98140 and 1507 maize, contains the genetic
elements introduced in the two maize: the gat4621, zm-hra, cry1F
and pat genes along with the regulatory elements for gene
expression.
· 98140x1507x59122 maize, obtained from traditional breeding
methods between progeny of 98140, 1507 and 59122 maize contains
the genetic elements introduced in the three maize: the gat4621,
zm-hra, cry1F, cry34Ab1, cry35Ab1 and pat genes along with the
regulatory elements for gene expression.
6. Brief description of the method
used for the genetic modification:
1507 maize was genetically modified
using a particle acceleration method.
Both 59122 maize and 98140 maize were genetically modified using
Agrobacterium transformation method.
No genetic modification was made on 98140x1507 and
98140x1507x59122 maize directly: they were derived through
traditional breeding methods from progeny of the genetically
modified 98140 and 1507 maize, or 98140, 1507 and 59122 maize,
respectively.
7. If the recipient or parental plant
is a forest tree species, describe ways and extent of
dissemination and specific factors affecting dissemination:
Not applicable.
Experimental Release
1. Purpose of the release:
The purpose of the deliberate
release program is to collect additional data on these
genetically modified maize. Studies will be carried out to
evaluate the expression of the introduced genes and the
composition, to observe the plant behavior, as well as the
herbicide application effects and the control of maize
volunteers with different herbicides.
2. Geographical location of the site:
In 2007, the release is planned at
the following locations in France: Fronton (31), Condom (32),
Ouzouer sous Bellegarde (45), Villeneuve sur Lot (47),
Mansonville (82), Valvidienne (86).
3. Size of the site (m2):
Every year, there could have up to
12 sites of release, each sown with up to 1000 m² of 1507 maize,
1000 m² of 59122 maize, 7000 m² of 98140 maize, 5000 m² of
98140x1507 maize, 5000 m² of 98140x1507x59122 maize.
4. Relevant data regarding previous
releases carried out with the same GM-plant, if any,
specifically related to the potential environmental and human
health impacts from the release:
Many field trials have already been
conducted at several locations across maize growing regions in
North America, as well as South America and Europe depending on
the maize, and no environmental problems were reported for these
trials. The transgenic plants are indistinguishable from the
non-genetically modified maize plants except for the traits due
to the genetic modifications (resistance to target Lepidopteran
insects such as European corn borer, and/or resistance to target
Coleopteran insects, such as Western corn rootworm, and/or
tolerance when glyphosate, ALS-inhibiting herbicides such as
sulfonylureas and/or glufosinate were applied).
Moreover, 1507 and 59122 maize are no more regulated in the USA
since 2001 and 2005, respectively, and thus are widely
commercialized in the USA.
Environmental Impact and Risk
Management
Summary of the potential environmental
impact from the release of the GMPts:
No risks to human and animal health or
the environment from the proposed deliberate release of 1507,
59122, 98140, 98140x1507, 98140x1507x59122 maize are expected,
as per information contained in the environmental risk
assessment included in the notification.
Brief description of any measures
taken for the management of risks:
The pollen shed from the genetically
modified plants will be controlled by maintaining a 200-meter
isolation distance with any other commercial maize crop. As it
is done for any trial with conventional maize, the trial site
will be surrounded by agronomic border rows of conventional
maize of a similar maturity. The agronomic border rows will be
also destroyed at the end of the release.
Seed dispersal of individual kernels does not generally occur.
They are fixed on a cob and enclosed in many husks that protect
the seeds from outside contact. When a few seeds need to be
collected for analysis, this will be done by sampling the whole
ear and unused seeds will be destroyed by incorporation into the
soil.
In case of an emergency, the trial could be destructively
stopped by mechanical destruction or application of a herbicide
other than glyphosate, ALS-inhibiting herbicides and
glufosinate-ammonium, and incorporation into the soil by a deep
ploughing.
At the end of the release, all remaining plant matter that has
not been harvested for analyses will be destroyed by chopping
and incorporating into the soil by a deep ploughing. No plant or
plant product coming from the trials will enter the food or feed
chains.
After the release, the site will be visited regularly during the
following year in order to ensure removal of maize volunteers,
if any. Although volunteer maize cannot generally survive hard
winter, maize volunteers, if any, will be monitored in order to
ensure their destruction.
No commercial maize crop will be planted on the same area the
following year.
Summary of foreseen field trial
studies focused to gain new data on environmental and human
health impact from the release:
Not applicable to this release.
Final report
-
European Commission administrative
information
Consent given by the Competent
Authority:
Not known |
