Chromatin Inc. appoints Dr. Mich Hein as President and CEO

Chicago, Illinois
January 7, 2003

Chromatin, Inc. today announced that its Board of Directors has appointed Dr. Mich Hein as President and CEO effective January 1, 2003. Prior to assuming his position with Chromatin, Dr. Hein founded Epicyte Pharmaceuticals (San Diego, California) where he served as Director and President for six years.

    "The Board and Founders of Chromatin are extremely pleased to have attracted someone of Mich's caliber to lead the development of Chromatin's exciting mini-chromosome technology," said Roger Wyse, Chairman of the Board of Chromatin. "Mich brings a unique combination of scientific knowledge, experience in leading a start up company, understanding of the market dynamics at the interface of agriculture, pharmaceuticals and industrial biotechnology as well as fundraising acumen. His track record in commercializing plant biotechnology is outstanding," added Wyse.

    Dr. Hein brings to Chromatin extensive business and relevant scientific experience as well as considerable scientific expertise in analytical chemistry, plant molecular biology, and immunology. At Epicyte, he managed the company's strategic business development, government relations and key commercial alliances, including relationships with the Dow Chemical Company and DowAgroSciences, Biovation, and the Centocor division of J&J.  Dr. Hein also directed Epicyte's research and development programs funded through DARPA, USAMRIID, and the NIH.

    Dr. Hein began his career as a research chemist at Monsanto, and subsequently managed the plant molecular biology research effort for PPG Industries in La Jolla, CA.  He left PPG to join the faculty of the Departments of Cell Biology and Molecular Biology at The Scripps Research Institute. In addition to his business experience, he is a pioneer in the
development of plants for production of antibodies, vaccine subunits and other high value proteins -- an area in which he is an inventor on numerous patents.

    Chromatin, Inc. is headquartered in Chicago, IL and was founded in 2000, based on technology developed in the laboratory of Dr. Daphne Preuss and her colleagues at the University of Chicago.  Chromatin's mini-chromosome technology is designed to significantly accelerate the pace of crop improvement, enabling the rapid delivery of large numbers of genes.  The company's suite of intellectual property enables the development of crops with improved genetics to enhance nutritional value, and food safety, and can accelerate the discovery and development of affordable pharmaceuticals and production of industrial and consumer products.

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