Princeton, New Jersey
February 17, 2000
Senesco
Technologies, Inc. announced today that it significantly delayed natural
leaf senescence (aging) in Arabidopsis plants (Arabidopsis thaliana) by reducing the expression of its
proprietary deoxyhypusine synthase (DHS) gene. This delayed senescence is accompanied by
substantially larger leaf size and provides strong indication of the ability to increase crop yield, a long
standing industry objective.
DHS is a regulating gene that triggers the initiation of senescence and significantly delays natural leaf
aging. This extension of plant life in the field is indicative of the ability to increase crop yield because
plants are able to invest more energy and resources to the production of seed. More or larger seed
results in higher yield and therefore, increased profit opportunity.
Ruedi Stalder, Chairman and Chief Executive Officer of Senesco commented, ``Senesco's proof of
concept indicates that silencing the DHS gene has broad based application because our results indicate
that this gene is involved in the initiation of senescence in all plant tissues. We are excited about this
breakthrough and the prospect of enhancing the yield of all horticultural and agronomic crops as a result
of these new developments.''
Senesco Technologies, Inc. is an agro-biotechnology company developing proprietary, patent-pending
genetic technologies designed to slow the rate of senescence, the natural cellular breakdown and aging
of plants and produce. The Company is exploring approaches for implementation of the technology by
conventional breeding. Senesco's technologies are applicable to prolonging the shelf life of plants and
produce, and to increasing the yield of crops by enhancing their lifespan and protecting them from
damaging environmental factors.
Company news release
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