Dr. Leo Kim, Chief Technical Officer at Akkadix, said that the grant
will support a research and software development program under the direction of principal
investigator Arcady Mushegian, Ph.D. It will be based on annotation strategies aimed at
improving the accuracy of methods used to analyze information on protein function.
"Several large scale sequencing projects have produced an
explosion of data, but previous automated methods of processing and organizing information
contained in these databases have not achieved the level of accuracy required to reliably
predict protein function," Kim said. "A Phase I study employing the methods Dr.
Mushegian's team is pursuing has resulted in an error rate of less than 5%, as compared to
error rates as high as 25% with some other methods.
Kim said that Akkadix is conducting beta tests of high throughput
software developed around refined annotation strategies employed in the Phase I study.
"Understanding and being able to accurately predict the
function of proteins is at the heart of applications of biotechnology in developing new
drugs, industrial enzymes and genetically enhanced plants," Kim said. "This
grant recognizes the promise our research holds for advancing this critical area of
science."
Akkadix applies advanced life science technologies to discover and
characterize novel genes that can be incorporated into plants to make them resistant to
disease and pests, increase plant vigor and productivity and enhance the quantity and
quality of agricultural outputs such as oil, starch, fiber and nutrient. The company also
maintains cooperative germplasm relationships with more than 25 companies around the
world.