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U.S. National Science Foundation awards 26 new grants to seed plant systems biology - Focus includes genome-enabled research in plants of economic value and development of novel tools

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Washington, DC
October 11, 2007

The U.S. National Science Foundation (NSF) has made 26 new awards totaling $85.8 million during the tenth year of its Plant Genome Research Program (PGRP).

These awards--which cover two to five years and range from $400,000 to $7.9 million--support research and tool development to further knowledge of genome structure and function. They will also increase understanding of gene function and interactions between genomes and the environment in economically vital crop plants such as corn, rice and cotton.

"Plant biologists continue to exploit genomics tools and sequence resources in new and innovative ways," said James Collins, NSF assistant director for biological sciences. "It's exciting to see research involving biologists and mathematicians, computer scientists and engineers, all working to address major unanswered questions in plant biology. These latest projects will also have a significant impact on how we train the next generation of plant scientists to carry out research at the cutting edge of the biological sciences."

The new awards--made to 45 institutions in 28 states--include international groups of scientists from Asia, Australia and Europe.

First-time recipients of PGRP awards include Auburn University, Dana-Farber Cancer Institute, SUNY Stony Brook, University of Alaska Fairbanks, University of Toledo, and University of Virginia.

The wealth of genomics tools and sequence resources developed over the past ten years of the PGRP have opened up exciting, new comparative approaches in plant biology. PGRP researchers continue to uncover gene networks that regulate plant development and growth in concert with environmental signals, such as temperature, light, disease and pests.

These projects include:

  • Researchers at the University of Alaska, Fairbanks are using poplar to develop population genetics tools to identify genes involved in phenotypic variation in bud set, a critical adaptive trait for cold tolerance and growth rate. This project is supported in part by the NSF Office of Polar Programs and includes collaborations with scientists in Canada and Sweden. 
  • A project led by Michigan State University is using a combination of computation and functional genomics resources to learn more about low-temperature regulatory networks and factors involved with freezing tolerance in tomato and potato. 
  • Washington State University is leading a project that uses biochemical genomics to reveal components of biosynthesis pathways necessary to produce novel fatty acids in oilseeds. Plants are natural producers of non-saturated fatty acids. 
  • A project led by Alabama A&M University is working to identify regulatory gene networks responsible for changes in gene expression in response to nematode infection in cotton plants.

PGRP is also continuing to support the development of tools to enable researchers to make breakthroughs in understanding the structure and function of economically important plants -- from the gene level to the whole plant.

Example projects include:

  • A multidisciplinary team of investigators at the University of Wisconsin-Madison will develop cutting-edge technology using cameras, robotics and computational tools to enable high-throughput analysis of traits in mutant or naturally varying plant populations.
  • A project led by the Dana-Farber Cancer Institute is using Arabidopsis and rice genomic resources to produce a plant "interactome," a map of all protein-protein interactions. This map will provide scientists with testable predictions of how genes and the proteins they encode interact to carry out complex functions within a plant cell.

The PGRP, which was established in 1998 as part of the coordinated National Plant Genome Initiative by the Interagency Working Group on Plant Genomes of the National Science and Technology Council, has the long-term goal of advancing the understanding of the structure and function of genomes of plants of economic importance.

Source: http://www.nsf.gov/bio/pubs/awards/pgr.htm

 

Plant Genome Comparative Sequencing Program: Awards
 
Fiscal Year 2007 Awards
Genome-Enabled Plant Research (GEPR)
Transferring Research From Model Systems(TRMS)
Tools and Resources for Plant Genome Research(TRPGR)
Award # Principal Investigator Institution Title Total Award ($) Total Duration (Yrs)
0605200 Bedinger, Patricia Colorado State University
University of Missouri-Columbia*
University of California-Davis*
Cornell University*
Ohio State University*
Using Genomic Tools to Identify Interspecific Reproductive Barriers in the Tomato Clade $3,904,788 4
0701297 Birchler, James University of Missouri-Columbia Maize Artificial Chromosomes $1,902,766 5
0701919 Browse, John Washington State University
Donald Danforth Plant Science Center*
Michigan State University*
SUNY Stony Brook*
Montana State University*
Biochemical Genomics: Quizzing the Chemical Factories of Oilseeds $4,574,645 4
0701757 Buerkle, C. Alex University of Wyoming Analytical Tools for Studies of the Genomics of Isolation between Plant Taxa $399,432 3
0701731 Evans, Matthew Carnegie Institute of Washington (CA)
South Dakota State University*
Oregon State University*
Iowa State University*
Functional Genomics of Maize Gametophytes $4,745,983 5
0701488 Folta, Kevin University of Florida
University of New Hampshire*
Identification and Functional Characterization of Novel Expressed Transcripts in the Rosaceae $1,005,853 3
0701871 Freeling, Michael University of California-Berkeley Computing Regulatory DNA by Comparing Plant Genomes $1,965,052 5
0605659 Giovannoni, James Boyce Thompson Institute for Plant Research
Colorado State University*
Cornell University*
U.S. Contribution to the International Solanaceae Genome Effort $1,800,000 2
0701405 Grotewold, Erich Ohio State University
University of Toledo*
The Grass Regulome Initiative: Integrating Control of Gene Expression and Agronomic Traits Across the Grasses $2,479,632 3
0703470 Kantety, Ramesh Alabama A&M University
Auburn University*
J. Craig Venter Institute*
University of Oklahoma-Norman*
Genomic Resources for the Study of Cotton-Reniform Nematode Interactions $1,047,574 3
0703273 McCarty, Donald University of Florida
Cold Spring Harbor Laboratory*
Iowa State University*
Construction of Comprehensive Sequence Indexed Transposon Resources for Maize $3,703,558 4
0701745 Meyers, Blake University of Delaware
University of California-Los Angeles*
Ohio State University*
Understanding the Rice Epigenome: From Genes to Genomes $5,313,292 4
0701736 Nelson, Timothy Yale University
Boyce Thompson Institute*
Cornell University*
Iowa State University*
Comparative Analysis of C3 and C4 Leaf Development in Rice, Sorghum and Maize $5,475,678 4
0701911 Olson, Matthew University of Alaska Fairbanks
University of Minnesota-Twin Cities*
Population Genomics of Cold Adaptation in Poplar $1,687,757 4
0702454 Pawlowski, Wojciech Cornell University Natural Variation in Meiotic Recombination in Maize $404,686 2
0701382 Purugganan, Michael New York University
Cornell University*
Purdue University*
Washington University*
The Evolutionary Genomics of Rice Domestication $4,402,973 4
0649614 Quackenbush, John Dana-Farber Cancer Institute Reconstruction and Annotation of Transcribed Sequences in Plants $2,566,000 4
0701119 Salt, David Purdue University
Dartmouth University*
Texas A&M Research Foundation*
Ionome to the Genome: Mapping the Gene Networks Controlling Nutrient Content in Rice Grain $5,323,284 4
0621702 Spalding, Edgar Univeristy of Wisconsin-Madison Machine Vision-Based Quantification of Plant Growth and Development $1,110,004 2
0703908 Stein, Lincoln Cold Spring Harbor Laboratory
Cornell University*
Gramene: A Platform for Comparative Plant Genomics $6,944,880 4
0701846 Sussman, Michael University of Wisconsin-Madison An Interdisciplinary Approach to Deciphering the Molecular Dialogue between the Plasma Membrane and Cytoplasm of Medicago truncatula $2,462,216 3
0701709 Thomashow, Michael Michigan State University
Oregon State University*
Low Temperature Transcriptional Networks $4,738,001 5
0703285 Udvardi, Michael Samuel Roberts Noble Foundation Development of Genetic Resources to Dissect Gene Regulatory Networks Governing Nodule Development and Differentiation in Medicago truncatula $3,831,732 4
0703905 Vidal, Marc Dana-Farber Cancer Institute
The Salk Institute for Biological Studies*
A Plant Interactome Network Map $7,971,396 4
0701880 Walbot, Virginia Stanford University
University of California-Berkeley*
Cell Fate Acquisition in Maize $4,577,530 5
0701748 Westwood, James Virginia Polytechnic Institute and State University
Pennsylvania State University*
University of California-Davis*
University of Virginia*
The Parasitic Plant Genome Project $1,528,815 3
 

 National Science Foundation
Plant Genome Research Program

Plant Genome Comparative Sequencing Program (PGCSP)

Award #

Principal Investigator

Institution

Title

Total Award ($)

Total Duration (Years)

0638566

Buckler, Edward

Cornell University

Cold Spring Harbor Laboratory*

High Density Scoreable Markers for Maize Trait Dissection

$963,016

2

0638591

Conner, Jeffrey

Michigan State University

Institute for Genomic Research*

Comparative cDNA Sequencing in Radish (Raphanus), a Crop, Weed, and Model System in Ecology and Evolution

$1,009,597

2

0638595

dePamphilis, Claude

Pennsylvania State University

University of Florida*

University of Georgia*

Washington University*

The Ancestral Angiosperm Genome Project

$3,087,691

2

0638558

Devos, Katrien

University of Georgia Research Foundation Inc

Institute for Genomic Research*
University of California-Davis*

Gaining Insight into the Organization and Evolution of Genomes Through Wheat - Brachypodium - Rice Comparative Analysis

$1,521,112

2

0638525

Meyers, Blake

University of Delaware

Comparative Sequencing of Plant Small RNAs

$1,034,253

2

0638502

Neale, David

University of California-Davis

Comparative Resequencing in the Pinaceae

$505,122

1

0638820

Olsen, Kenneth

Washington University

University of Arkansas*

University of Massachusetts Amherst*

The Evolutionary Genomics of Invasive Weedy Rice

$1,121,523

2

0638536

Pires, J. Chris

University of Missouri-Columbia

Institute for Genomic Research*
University of Georgia Research Foundation Inc*

Toward Unraveling the Morphological Plasticity and Genome Redundancy of Brassica Oleracea

$1,544,477

2

0638418

Wendel, Jonathan

Iowa State University

University of Arizona*

University of Georgia Research Foundation Inc*

Genome Evolution in Diploid and Polyploid Cotton

$1,543,966

2

0638541

Wing, Rod

University of Arizona

Cold Spring Harbor Laboratory*

Purdue University*

Sequencing of Chromosome 3 Short Arms From the AA, BB, CC, BBCC Genomes of Wild Relatives of Rice for Comparative Functional and Evolutionary Genomics

$2,735,151

2



 

 

 

 

 

 

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