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Plant Health Care and Monsanto sign agreement for the development and commercialization of
Harpin-based technology

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Pittsburgh, Pennsylvania and St. Louis, Missouri
December 12, 2007

Plant Health Care Inc, a wholly-owned subsidiary of Plant Health Care plc (AIM: PHC), and Monsanto Company (NYSE: MON) have entered into an agreement to evaluate, develop and commercialize applications of Plant Health Care’s Harpin-based technology.

Plant Health Care’s Harpin seed technology is aimed at suppressing nematodes in crop settings. Under the
agreement, Plant Health Care will grant Monsanto certain exclusive rights to applications of its Harpin technology. In return Plant Health Care will receive an undisclosed upfront payment, plus a milestone payment dependent upon the progress of the development of the technology over the next twelve months.

Once evaluations are complete, the companies estimate that the products could be available to farmers by
the end of the decade. At the time of commercialization, Plant Health Care will also receive a royalty payment based on the acreage for which the Harpin technology is supplied. Additional terms of the agreement were not disclosed at this time.

John Brady, CEO of Plant Health Care, noted: “This agreement represents a significant step forward in the
development of our company and provides an ideal first platform for the Harpin technology. This agreement with Monsanto validates the confidence that our Board has in the Harpin technology which we only acquired earlier this year.”

Monsanto Company is a leading global provider of technology-based solutions and agricultural products that improve farm productivity and food quality.

Plant Health Care plc (“PHC”) is a leading provider of natural products for plants and soil. Established in 1995 in Pittsburgh (Pennsylvania) in the United States, PHC currently has approximately 70 employees and has operations in the United States, Mexico, the United Kingdom, Spain, and the Netherlands. The Company listed on the AIM market of the London Stock Exchange in July 2004. Ticker symbol is PHC. PHC’s products are aimed at the landscape, agriculture and land reclamation industries and are environmentally beneficial. Through the commercialization of these products, PHC is capitalizing on current long-term trends toward natural systems and biological products for plant care and soil and water
management.

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