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Building disease-beating wheat

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Australia
December 12, 2007

Disease resistance genes from three different grass species have been combined in the world’s first ‘trigenomic’ chromosome, which can now be used to breed disease resistant wheat varieties.

Pioneered by CSIRO researchers, in collaboration with the International Maize and Wheat Improvement Center (CIMMYT) and Sydney University, the research illustrates the major genetic improvements possible without genetic modification (GM) technology.

“Wheat breeders often use wild relatives of wheat as sources of novel genes in breeding new disease-resistant wheats,” research team leader Dr Phil Larkin says.

“The exciting part of the new research is that we have been able to retain the useful genes but leave behind the associated undesirable genes - most notably in this case those for yellow flour colour, an important quality characteristic in wheat,”

Dr Larkin says.“Unfortunately genes from wild relatives usually come in large blocks of hundreds of genes, and often include undesirable genes. Furthermore, these blocks of genes tend to stay together, even after many generations of breeding.

“The problem can be so difficult to overcome that plant breeders sometimes give up on very valuable genes because they cannot separate them from the problematic genes.”

A paper published this month in the respected international journal Theoretical and Applied Genetics details how the team ‘recombined’ two wild blocks of genes from two different Thinopyrum grass species – a wild relative of wheat – bringing together resistance genes for leaf rust and Barley Yellow Dwarf Virus (BYDV), two of the world’s most damaging wheat diseases. The recombined gene ‘package’ may also carry a resistance gene against a new stem rust strain which is causing concern worldwide.

By developing new ‘DNA markers’ and by careful testing the team has produced a number of the disease resistance ‘packages’ for wheat breeders, making it faster and easier to include these important disease resistance traits in future wheat varieties.

It is hoped other examples will follow and the genetic diversity available in wild species can be recruited more extensively for wheat improvement.
 

Fighting off the yellow dwarf
Learn how the world’s first’ trigenomic’ chromosome can be used to breed wheat varieties resistant to diseases like Barley Yellow Dwarf Virus and leaf rust.

http://www.csiro.au/multimedia/YellowDwarfVirus.html

The world’s first trigenomic chromosome has been developed, using the disease resistance genes from three different grass species.

The chromosome was pioneered by CSIRO researchers, in collaboration with the International Maize and Wheat Improvement Center (CIMMYT) and Sydney University.

A paper published this month in the respected international journal Theoretical and Applied Genetics details how the team ‘recombined’ two wild blocks of genes from two different Thinopyrum grass species – a wild relative of wheat – bringing together resistance genes for leaf rust and Barley Yellow Dwarf Virus (BYDV), two of the world’s most damaging wheat diseases.

In this podcast, research team leader, Dr Philip Larkin explains how the trigenomic chromosome was created.

Other news from CIMMYT / from Sydney University

 

 

 

 

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