Source: Proceedings of the National Academy of Sciences of the United States of America (PNAS)

Complex genetic networks underlying the defensive system of rice (Oryza sativa L.) to Xanthomonas oryzae pv. oryzae
Z. K. Li, M. Arif, D. B. Zhong, B. Y. Fu, J. L. Xu, J. Domingo-Rey, J. Ali, C. H. M. Vijayakumar, S. B. Yu, and G. S. Khush
Institute of Crop Sciences/National Key Facility for Crop Gene Resources and Genetic Improvement, Chinese Academy of Agricultural Sciences, Beijing 100081, China; and International Rice Research Institute, DAPO Box 7777, Metro Manila, Philippines
Edited by Frederick M. Ausubel, Harvard Medical School, Boston, MA, and approved February 5, 2006 (received for review September 2, 2005)
PNAS published 15 May 2006, 10.1073/pnas.0507492103 Open Access
OPEN ACCESS ARTICLE
http://www.pnas.org/cgi/content/abstract/0507492103v1?etoc

ABSTRACT

Complete resistance (CR) and partial resistance (PR) of rice (Oryza sativa L.) to its bacterial pathogen, Xanthomonas oryzae pv. oryzae (Xoo), was genetically dissected by using 2 mapping populations and 10 Xoo races. Two CR genes, 50 quantitative resistance loci, and 60 digenic interactions were identified, which showed various degrees of race specificity to the Xoo races. The complex epistasis between these loci led us to the discovery of complex genetic networks underlying the rice defensive system to Xoo. The networks consisted of two major components: one representing interactions between alleles at the R loci of rice and alleles at the corresponding avirulence loci of Xoo for CR and the other comprising interactions between quantitative resistance loci in rice and their corresponding aggressiveness loci in Xoo for PR. The race specificity of PR and its strong genetic overlap with CR indicate that PR is essentially "weaker" CR. The genetic networks discovered are expected to maintain a high level of the allelic diversity at avirulent loci in the pathogen by stabilizing selection, which may maintain a high allelic diversity at R loci in the host by the frequency-dependent selection.

Source URL: http://www.pnas.org/cgi/content/abstract/0507492103v1?etoc