Coventry, United Kingdom
June 2, 2005
Researchers at the
University of Warwick's
horticultural research arm Warwick HRI have created an extensive
new range of libraries of plant DNA that will provide a massive
boost to the world's plant researchers. The new collection of
DNA libraries is the largest of its type in the world and will
provide researchers with a unique resource.
The Warwick researchers have set up a new spin out company "Warwick
Plant Genomic Libraries Limited" to develop this powerful
new resource for plant researchers. It will be of particular
benefit to academic researchers, scientists working in
agriculture and horticulture and also to pharmaceutical research
teams interested in the medicinal properties of plants.
The new libraries have two key features that will make them
particularly attractive to researchers. Firstly, there are
genomic libraries from 20 different plant species, a far wider
range than is available from other DNA library services.
Secondly, the Warwick researchers have been able to create plant
DNA libraries with large and "unbiased" inserts that give the
best possible representation of the DNA of each species. Genomic
DNA libraries usually employ "restriction enzymes" to cut up the
DNA but this method may preferentially select only certain
regions of DNA and exclude other regions from the final plant
"library". The techniques used by the Warwick researchers remove
this limitation and make the plant's entire DNA available to
researchers.
The new plant DNA libraries include:
Aloe Vera - a plant with interesting medicinal
properties and a DNA structure made up of 16,000 megabases (by
comparison a human's DNA structure consists of 3,000 megabases)
Catharanthus roseus - a plant which is the only
source of two key drugs (vincristine and vinblastine) used in
the treatment of a number of cancers.
The library also includes: Apple, Banana, Foxglove, Mint, Olive,
Orange, Pineapple, Evening Primrose, Strawberry, Sunflower,
Cocoa, Coffee, Ginger, Ginkgo, Ginseng, Grape, Tea and Yew. The
company can also create custom DNA libraries for other specific
plant species that researchers wish to examine. Further details
can be found on the new company's web site:
http://www.wpgl.co.uk/ |