October 27, 2003
from
New Zealand Herald via
Checkbiotech.org
Scientists
have genetically modified a potato to produce a protein that
helps the body to repair itself after surgery. A team from
Singapore Polytechnic and
The New Zealand Institute of Crop and
Food Research
says the protein is so valuable that the potatoes could be grown
only in containment - avoiding worries about genes "escaping"
into the environment.
Crop and
Food scientist Tony Conner said in April that each gram of the
protein, extracted from about seven potato plants, was worth
about $1 million.
"We can make a synthetic gene and transfer it into potatoes,
and the potatoes produce the protein," he said this week.
"We have been able to extract it and purify it. The issue is
whether there is sufficient protein to scale it up and go to the
next level."
The protein helps the body repair itself after heart or
circulatory system surgery or nervous diseases.
The idea of making it in potatoes dates from the early 1990s,
when Singaporean student Oi Wah Liew did her doctorate at
Lincoln University near Christchurch, where Conner is a
part-time professor.
Liew is now a lecturer at Singapore Polytechnic, but returns to
Lincoln once a year to work on the potato project. In 1999 she
told a German news agency that she took the gene from a rat and
used it in potatoes to make a hormone called atrial natriuretic
factor, which occurs in the hearts of humans and other mammals.
At present, the only source of the substance for medical use is
from dead human bodies.
Conner said that now that the technology was proven in
potatoes, he and Liew might try to duplicate it in a non-food
crop such as tobacco in order to reduce public concerns about
tampering with a staple food.
The institute is developing other plants with health properties
such as boosting selenium, a trace element in soils which helps
people to stave off heart disease and HIV/Aids. It is deficient
in many soils in New Zealand, China and elsewhere.
"We are trying to understand the nature of selenium
accumulation and uptake in plants and whether we can improve
that by management or classical breeding or whether it might be
a GM approach," Conner said.
"We are trying to use genes from some of the brassicas because
they are known to be accumulators."
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